ABSTRACT
Objective To observe the effect of herbal treatment to strengthen spleen,tonify kidney,invigorate blood flow and dissolve phlegm plus Rosiglitazone on nonalcoholic fatty liver disease (NAFLD) with insulin resistance (IR).Methods The 90 cases were randomized into 3 groups:blank group of 29 cases;western medicine group of 32 cases,treated with Rosiglitazone;treatment group of 29 cases treated with herbal medicine plus Rosiglitazone.The changes in liver function,blood lipid,fasting blood glucose (FBG),fasting insulin (FIN),insulin resistance index (IRI),serum leptin and adiponcetin were observed.Results In the treatment group,changes of liver function,blood lipid,FBG,FIN,IRI,serum leptin and adiponcetin compared after treatment was significant (P